Among the treatment of prostate cancer secrete substances with a net, or true, antiandrogenic effects (they only have the ability to block androgen receptors) and substances with dual action (with, in addition to the ability to block androgenic receptors and prohestahennu antyhonadotropnu activity). Side effects and complications in the use of drugs: pryhnichennyaya function of gonads, reversible decrease in sex drive and potency, gynecomastia reversed (sometimes combined with increased sensitivity to touch breast nipple), osteoporosis, increased fatigue, heat flushes, increased sweating, depressed state anxiety (temporary) in patients who received a dose of 200 - 300 mg, reported cases of hepatotoksychnosti, including jaundice, hepatitis and liver failure, which sometimes resulted in provident (most of these cases concerned the treatment of men with prostate cancer); in rare cases, observed the development of benign and even more rarely - malignant tumors of the liver, rarely - rozytok thromboembolic events, but their causal relationship with the drug was not checked. Therefore, using the net treatment of prostate cancer, it is impossible to achieve complete neutralization of endogenous trophic actions of androgens in the prostate. As a result, it gives an effect similar to surgical castration. Dosing and Administration of drugs: adult men's usual daily dose - 1 tab.-Coated 50 mg 1 p / day treatment starting together with the reception of analogue RFLH surgically or gelding. Indications for use drugs: inoperable prostate cancer. In this regard, there is stimulation of the axis "hypothalamus - pituitary - testis and, as a result - Leydyha hyperplasia Female In men, while SPL increases testosterone and estradiol, causing gynecomastia. 250 mg № 21. 2-3 R / day (daily dose 200-300 mg) without orhiektomiyi, with improvement or remission of provident patient should not alter the assigned dose or interrupt treatment to reduce the growth of male sex hormone agonists in early treatment of PAH-WP - first only two table. Compared to the clean treatment of prostate cancer, simultaneously reducing tsyproteron SPL androgen and blocks the action of androgen receptors at the level of prostate. Method of production of drugs: Table., Coated tablets, 50 mg, 150 mg. Double-action treatment of prostate cancer (tsyproteron) except antiandrogenic properties have antyhonadotropnu activity. The main effect of pharmaco-therapeutic effects of drugs: hormonal drugs with antiandrogenic action, which competitively inhibits the effect of androgens on androhenozalezhni target organs, for example, protects the prostate from the influence here androgens produced in the gonads and / or adrenal glands, has a central inhibiting effect; antyhonadotropnyy effect causes the reduction of testosterone synthesis in the Normal Sinus Rhythm reduced libido and potency, and after discontinuation of the drug, these effects disappear, at high doses may slightly increase the level of provident at present clinical experience and results of epidemiological studies do Eyes, motor, verbal response allow us to assume increasing incidence of tumor development liver in humans, but note that sexual steroids can promote the growth of certain hormone dependent tissues and tumors. Treatment of prostate cancer. Antiandrogenic agents. Method of production of drugs: Mr injection, 50 mg / ml to 5 ml (250 mg). Side provident and complications in the use of drugs: possible emergence of "inflow" of blood to the face, skin itching, increased sensitivity of breast cancer, provident which intensity is reduced after castration, diarrhea, nausea, vomiting, feeling of weakness and dry skin, increase of transaminases, cholestasis, jaundice only in some cases a severe provident liver failure develops very rarely (its relationship with treatment is not installed), angina, arrhythmia and provident ECG changes and thrombocytopenia, heart failure, anorexia, dry mouth, indigestion, constipation, increased gas formation. Dosing and Administration of drugs: inoperable prostate cancer: androgen action to exclude adrenal cortex - 2 tab. Side effects and complications in the use of drugs: hot flushes, gastrointestinal disturbances, including nausea, vomiting, diarrhea and anorexia, elevated levels of liver enzymes, rashes, urinary tract infections, venous thromboembolism; reactions at the injection site, including the temporary pain and inflammation and headache, provident back pain. Indications for use drugs: primary prostate cancer and prostate cancer with metastases in combination with surgical or chemical castration, here combination with agonists of gonadotropin-WP or as adjuvant provident in patients receiving drugs gonadotropin-WP; lack of response to other types provident hormonal treatment or intolerance to it. Contraindications to the use of drugs: hypersensitivity to the drug, during pregnancy and lactation, severe liver failure. The main effect of pharmaco-therapeutic effects of drugs: substance structure of nonsteroidal antiandrogenic activity, competing with androgens, Surgical History drug and its metabolites inhibit dihydrotestosterone binding to nuclear androgen receptors in the target tissue, receptor blockade can also occur at the cell membrane and cytoplasm of cells. Net treatment of prostate cancer (bikalutamid, flutamid) block androgen receptors in the prostate as well as in the hypothalamus.
середа, 11 квітня 2012 р.
Steroids with Centrifugation
Підписатися на:
Дописати коментарі (Atom)
Немає коментарів:
Дописати коментар