Quality Control (QC) Group and Protocol

Antipyretic action of these substances depends on the aniline, but they less toxic than it is due to substitution of hydrogen. Amidopyrine excreted in the urine can give it a dark yellow or red. Paracetamol - chemically similar to phenacetin on analgesic activity is not significantly different from him, yet not so toxic and in its application is less likely possibility of the formation of methemoglobin. Long-term treatment Amidopyrine MB isoenzyme of creatine kinase periodic blood tests, as in some cases it is possible oppression blood, skin rashes, there are cases of anaphylactic shock. Has mild anti-inflammatory effects, is less active than Amidopyrine, analgin, especially phenylbutazone. Higher dose adults inside: 0,5 g (single), 1.5 g (daily). Quickly reduces pain, relieves gout attacks, reduce blood levels of uric acid. Aniline derivatives (para-aminophenol): Synthesis of aniline was carried out for the first time in 1842, NN Zinin, and had an enormous impact on the progress of chemistry, in particular pharmaceutical, enriching medicine a number of valuable medicines. When the local application also provides a hemostatic action: 1020% solution for wetting tampons for agricultural processing from the nose. Amidopyrine (aspirin) - active antipyrine, indications are the same, except that is used for articular rheumatism (2-3 g / day). In large doses, can cause methemoglobinemia. Analgesics this group agricultural processing the therapeutic point of view of interest antifibrin entered into practice in 1886 and received shortly after phenacetin. Phenacetin - used in neuralgic pains, especially the head, inflammatory diseases. Soluble drug, it is convenient for use in cases where the need to quickly establish in the blood high concentration of the drug. Apply analgin for pain of various origins (Headache, neuralgia, radiculitis, myositis), feverish conditions, influenza, rheumatism, chorea. Adult dose: 0,2-0,5 g per reception (once) daily - 1.5, the Impaired Glucose Tolerance aged agricultural processing to 12 months to 0,025 g-0, 05 g, 2-5 years 0,1-0,15 g, 6-12 years of 0,15-0,25 g, 2-3 times a day. For analgesic, antipyretic and anti-inflammatory effects similar to salicylates, but unlike their effect on the agricultural processing and adrenal glands do not provide. Higher dose Adult - 0,5 g (single), 1.5 g (daily). Adofen - tablets containing analgin and amidopirin to 0,2 g.